Article: A potential role for astrocytes in mediating the antiepileptic actions of furosemide in vitro.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Barbaro NM; Takahashi DK; Baraban SC Neuroscience, 2004
Table 1Intrinsic neuronal properties with 2.5 mM furosemide exposurea
aData are presented as means±S.E.M. Significance taken as P<0.05 using a two-way ANOVA analysis.
Cell type | N | RMP (mV) | Rin (MΩ) | AP height (mV) | AP duration (ms) | Time constant (ms) |
CA1 pyramidal | 6 | |||||
Baseline | −66.5±0.5 | 241.1±43.2 | 66.9±3.2 | 3.22±0.67 | 21.5±2.5 | |
Furosemide | −67.0±0.5 | 228.4±12.6 | 64.7±3.4 | 3.54±0.61 | 22.7±2.4 | |
L-M interneuron | 5 | |||||
Baseline | −68.2±1.6 | 292.4±33.2 | 58.6±2.4 | 2.32±0.24 | 19.0±3.6 | |
Furosemide | −70.5±3.2 | 284.7±33.4 | 58.7±3.0 | 2.56±0.19 | 17.2±3.0 |